Other Uses from Wikipedia

While Naltrexone has been studied for other uses, the ONLY "on-label" prescription is for alcohol or narcotic addiction.

Low dose naltrexone (LDN)
Low dose naltrexone (LDN), where the drug is used in doses approximately one-twelveth those used for drug/alcohol rehabilitation purposes, is being used by some as an "off-label" experimental treatment for certain immunologically-related disorders, including HIV/AIDS, multiple sclerosis (in particular, the primary progressive variant,) Parkinson's disease, cancer, fibromyalgia, autoimmune diseases such as rheumatoid arthritis or ankylosing spondylitis, Crohn's disease, ulcerative colitis, Hashimoto's thyroiditis, and central nervous system disorders.

Multiple Sclerosis
LDN is a treatment method that has been in use in the USA since 1985. It is showing to help neuromuscular spasm and fatigue. Also patients who are in the middle of an acute relapse when they start LDN have generally shown rapid resolution of the attack.

Reports show that 98 to 99% of people with MS on LDN experience no further disease progression in both relapsing-remitting and chronic progressive MS. Dr. Bihari has more than 70 people with MS in his practice and all have been stable over an average of three years. The original patient who used this therapy has been taking the drug for 19 years. In addition, more than 2000 people with MS within the United States, have been prescribed LDN by their own doctors.

MS Side-effects:
At high dose (150mg+) the drug has a number of significant side-effects. At the recommended dose of 3 to 4.5mg, no significant side-effects have been reported. It should be noted that this treatment is discouraged in those people still receiving beta interferon. Because LDN stimulates the immune system and beta interferon suppresses it, the two therapies can counteract each other.

Sexual dysfunction
Naltrexone can induce early morning erections in patients who suffer from psychogenic erectile dysfunction. The exact pathway of this effect is unknown.

Naltrexone has been shown to be effective in the reversal of sexual satiety and exhaustion in male rats.

Tobacco study
The Chicago Stop Smoking Research Project at the University of Chicago studied whether naltrexone could be used as an aid to quit smoking. The researchers discovered that Naltrexone improved smoking cessation rates in women by fifty percent, but showed no improvement for men.

Use for Crohn's disease
In a clinical trial conducted by Pennsylvania State University, it was concluded that low dose naltrexone helped people with Crohn's disease, putting the disease into remission in over two thirds of the cases studied. This was the stated conclusion: 'LDN therapy appears effective and safe in subjects with active Crohn's disease. Further studies are needed to explore the use of this compound.'

Self-injurious behaviors and Autism
Some studies suggest that self-injurious behaviors present in developmentally disabled and autistic people can sometimes be remedied with naltrexone. In these cases, it is believed that the self-injury is being done to release beta-endorphin, which binds to the same receptors as heroin and morphine. By removing the "rush" generated by self-injury, the behavior may stop.

Kleptomania
There are indications that naltrexone might be beneficial in the treatment of kleptomania (compulsive stealing).

Study in overweight and obese patients
Participants are being recruited for a study of the effects of Naltrexone therapy in overweight and obese patients.

Autism
Dr. Jaak Panksepp of Washington State University has conducted studies using naltrexone to treat patients with autism. He found that half the autistic children treated with the drug become more social.